學歷
學校 系所 學位
輔仁大學 化學研究所 博士
高雄醫學院 化學系 學士
經歷
期間 單位 部門 職稱
2020.8~2023.7 輔仁大學 化學系 系主任
2020.8~ 科技部 化學學門分析小組 學術委員
2018.8~2020.7 輔仁大學 環安衛中心 主任
2017.8 輔仁大學 化學系 教授
2012.8 輔仁大學 化學系 副教授
2012.8 輔仁大學 化學系 副教授
2009~ 輔仁大學 化學系 助理教授
2009~ 輔仁大學 化學系 助理教授
2008 國家衛生研究院 環境衛生與職業醫學組 博士後研究
2008 國家衛生研究院 環境衛生與職業醫學組 博士後研究
專長
質譜分析
電化學
生化與環境分析化學
質譜分析
電化學
生化與環境分析化學
學術著作
期刊論文
期間 內容
2023-11 Yi-Hsuan Hsieh, Wei-Ting Jung, Hui-Ling Lee* ,“Novel vinylene-based covalent organic framework as a promising adsorbent for the rapid extraction of beta-agonists in meat samples”, Analytica Chimica Acta 2023,1272, 341492. https://doi.org/10.1016/j.aca.2023.341492 (通訊作者, SCI, impact factor: 6.1, Ranking (Chemistry, Analytical): 8/86 = 9.30 % (Q1), 5-Year IF: 6.2). Times cited: 0.
2023-09 Chao-Lin Chung, Tsung-Ting Shih, Hui-Ling Lee* “Development of a novel vinylene-linked covalent organic framework decorated with multi-walled carbon nanotubes for electrochemical detection of tryptophan, uric acid, and 8-hydroxy-2′-deoxyguanosine”, Journal of the Chinese Chemical Society 2023, 1–11. https://doi.org/10.1002/jccs.202300184 (通訊作者, SCI, impact factor: 1.8, Ranking (Chemistry, Multidisciplinary): 123/178 = 75.42 % (Q3), 5-Year IF: 1.8). Times cited: 0.
2023-08 Wei-Ting Jung, Yi-Hsuan Hsieh, Yen-Jung Kuo, Yuan-Hsiang Yu, Yen-Hsiang Liu, Kuang-Lieh Lu, Hui-Ling Lee* “Rapid microwave synthesis of MOF microrods: dispersive SPE coupled with UHPLC–MS/MS to determine fluoroquinolones in honey”, Talanta, 2023, 263 124733 (通訊作者, SCI, impact factor: 6.1, Ranking (Chemistry, Analytical): 9/86 = 10.46 % (Q1), 5-Year IF: 6.1). Times cited: 0.
2023-06 4. Chien‑Yu Lin, Hui‑Ling Lee, Ching‑Way Chen, Chikang Wang, Fung‑Chang Sung6 and Ta‑Chen Su, “The role of angiotensin I-converting enzyme gene polymorphism and global DNA methylation in the negative associations between urine di-(2-ethylhexyl) phthalate metabolites and serum adiponectin in a young Taiwanese population” Clinical Epigenetics, 2023, 15:87, Ranking (GENETICS & HEREDITY): 25/171 = 14.62 % (Q1), 5-Year IF: 5.70). Times cited: 0
2023-05 李慧玲,'Global DNA methylation and the association between metal exposure and chronic kidney disease',Frontiers in Public Health,vol11.https://doi.org/10.3,2023-05
2023-02 李慧玲,'Possible Combined Effects of Plasma Folate Levels, Global DNA Methylation, and Blood Cadmium Concentrations on Renal Cell Carcinoma',Nutrients,vol15.937,2023-02
2023-01 ,'Determination of potential sources of heavy metals in patients with urothelial carcinoma in central Taiwan: a biomonitoring case–control study',Environmental Geochemistry and Health,volASAP.ASAP,2023-01
2022-08 ,'Global DNA methylation mediates the association between serum perfluorooctane sulfonate and carotid intima-media thickness in young and middle-aged Taiwanese populations',Ecotoxicology and Environmental Safety,vol241.113782,2022-08
2022-06 李慧玲,'Relationships of multiple metals exposure, global DNA methylation, and urothelial carcinoma in central Taiwan',Archives of Toxicology,vol96.1893-1903,2022-06
2022-03 ,'Soybean Meal Extract Preserves Memory Ability by Increasing Presynaptic Function and Modulating Gut Microbiota in Rats',Molecular Neurobiology,vol59.1649-1664,2022-03
2022-02 ,'Global DNA methylation mediates the association between urine ono-2-ethylhexyl phthalate and serum apoptotic microparticles in a young Taiwanese population',Science of the Total Environment,vol808.152054,2022-02
2021-12 ,'Association between the total plasma isomers of per- and polyfluoroalkyl substances and erythrograms in young and middle-aged Taiwanese population',Ecotoxicology and Environmental safety,vol227.112902,2021-12
2021-09 康智淵,郭彥嶸,'Polydopamine and silica nanoparticles magnetic solid phase extraction coupled with liquid chromatography-tandem mass spectrometry to determine phenolic acids and flavonoids in fruit wine',Journal of Food and Drug Analysis,vol29.391-401,2021-09
2021-06 榮偉廷,'Lipid peroxidation metabolites associated with biomarkers of inflammation and oxidation stress in workers handling carbon nanotubes and metal oxide nanoparticle',nanotoxicology,vol15.577-587,2021-06
2020-12 李慧玲,榮偉廷,郭彥嶸,'Relationships among cigarette smoking, urinary biomarkers, and urothelial carcinoma risk: a case-control study',Environmental Science and Pollution Research,vol27.43177–43185,2020-12
2020-11 李慧玲,吳仁瀚,'Determination of sunset yellow and tartrazine in drinks using screen-printed carbon electrodes modified with reduced graphene oxide and NiBTC frameworks',Microchemical Journal,vol158.105133,2020-11
2020-11 李慧玲,'Urinary heavy metals, DNA methylation, and subclinical atherosclerosiss',Ecotoxicology and Environmental Safety,vol204.111039,2020-11
2020-10 李慧玲,'The association between urine di-(2-ethylhexyl) phthalate metabolites, global DNA methylation, and subclinical atherosclerosis in a young Taiwanese',Environmental Pollution,vol265.114912,2020-10
2020-09 榮,'The association between urinary levels of 1,3-butadiene metabolites, cardiovascular risk factors, microparticles, and oxidative stress products in adolescents and young adults',Journal of Hazardous Materials,vol396.22745.,2020-09
2020-07 李慧玲,陳志昇,李懿,'Multiwalled carbon nanotubes /reduced graphene oxide nanocomposite electrode for electroanalytical determination of bisphenol A, 8-hydroxy-2’-deoxyguanosine and hydroquinone in urine',International Journal of Environmental Analytical Chemistry.774-788,2020-07
2020-03 李慧玲,'The association between total serum isomers of per- and polyfluoroalkyl substances, lipid profiles, and the DNA oxidative/nitrative stress biomarkers in middle-aged Taiwanese adults',Environmental Research.109064-109070,2020-03
2019-12 李慧玲,'Longitudinal follow-up of health effects among workers handling engineered nanomaterials: a panel study',Environmental Health,vol18.107,2019-12
2019-09 李慧玲,'SEPT14 Mutations and Teratozoospermia: Genetic Effects on Sperm Head Morphology and DNA Integrity',Journal of Clinical Medicine,vol8.1297,2019-09
2019-07 李慧玲,榮偉廷,'Measurement of urinary arsenic profiles and DNA hypomethylation in a case-control study of urothelial carcinoma',Archives of Toxicology.2155–2164,2019-07
2018-08 李慧玲,'Investigating the association between urinary levels of acrylonitrile metabolite N-acetyl-S-(2-cyanoethyl)-L-cysteine and the oxidative stress product 8-hydroxydeoxyguanosine in adolescents and young adults',Environmental Pollution 239 (2018) 493e498,vol239.493-498,2018-08
2018-02 李慧玲,康智淵,沈仁祥,'Rapid analysis of traditional Chinese medicine Pinellia ternata bymicrochip electrophoresis with electrochemical detection',J Sep Sci,vol41.740-746,2018-02
2017-08 李慧玲,'Targeted lipidomics profiling of acute arsenic exposure in mice serum by on-line solid-phase extraction stable-isotope dilution liquid chromatography–tandem mass spectrometry',Archives of Toxicology,vol91.3079-3091,2017-08
2017-04 李慧玲,陳昭宇,'Involvement of the cytokine–IDO1–AhR loop in zinc oxide nanoparticle-induced acute pulmonary inflammation',Nanotoxicology,vol11.360-370,2017-04
2017-03 李慧玲,陳昭宇,'Positive Association between Urinary Concentration of Phthalate Metabolites and Oxidation of DNA and Lipid in Adolescents and Young Adults',Scientific Reports,vol7.44318-44328,2017-03
2017-03 李慧玲,'Global DNA methylation and oxidative stress biomarkers in workersexposed to metal oxide nanoparticles',Journal of Hazardous Materials,,vol331.329– 335,2017-03
2017-02 李慧玲,陳志昇,'Relationships among DNA hypomethylation, Cd, and Pb exposure and risk of cigarette smoking-related urothelial carcinoma',Toxicology and Applied Pharmacology,vol316.107-113,2017-02
2016-09 李慧玲,林瑜雯,'Simultaneous, rapid, and sensitive quantification of 8-hydroxy-2′-deoxyguanosine and cotinine in human urine by on-line solid-phase extraction LC-MS/MS: correlation with tobacco exposure biomarkers NNAL',Analytical and Bioanalytical Chemistry,vol408.6295–6306,2016-09
2016-07 李慧玲,'Changes of serum amino acid profiles by epidermal growth factor receptor mutation and benzo[a]pyrene in mouse lung tumorigenesis',Toxicology Research,vol2016, 5.1182-1192,2016-07
2016-03 陳志昇,陳玉承,'Increased levels of oxidative stress biomarkers in metal oxides nanomaterial-handling workers',Biomarkers.1-7,2016-03
2015-01 李慧玲,Wen-Chieh Chiang,Chao-Yu Chen,'Fast and simple screening for the simultaneous analysis of seven metabolites derived from ?ve volatile organic compounds in human urine using on-line solid-phase extraction coupled with liquid chromatography-tandem mass spectrometry',Talanta,vol132.469–478,2015-01
2015-01 李慧玲,陳志昇,鐘思堯,'Disturbances to neurotransmitter levels and their metabolic enzyme activity in a freshwater planarian exposed to cadmium',NeuroToxicology,vol47.72-81,2015-01
2014-11 李慧玲,Kao-Lu Pan,Wei-Jan Huang,,Ming-Hua Hsu,Huei-Ju Liu,Chia-Wei Cheng,Ming-Hsien Tsai,Mei-Ya Shen,Pinpin Lin,'Identi?cation of trans , trans -2,4-Decadienal metabolites in mouse and human cells using liquid chromatography ? mass spectrometry',Chem. Res. Toxicol,vol27..1707-171,2014-11
2014-07 李慧玲,'Cadmium Neurotoxicity to a Freshwater Planarian',Arch Environ Contam Toxicol,,vol67.639-650,2014-07
2014-06 李慧玲,Chao-Yu Chen,Hao-I Cheng,Pinpin Lin,Ming-Hsien Tsai,Huei-Ju Liu,'Metabolomic profiling of mice urine and serum associated with trans - trans 2, 4-decadienal induced lung lesions by liquid chromatography-mass spectrometry',Anal Bioanal Chem,vol406.4287-4297,2014-06
2014-04 Hui-Ling Lee,Chien-Cheng Jung,Hsiu-Hao Liang,Nai-Yun Hsu,Huey-Jen Su,'Allostatic Load Model Associated with Indoor Environmental Quality and Sick Building Syndrome among Office Workers',PLOS ONE,vol9,2014-04
2013-01 Chi-Jung Chung,Yeong-Shiau Pu,Horng-Sheng Shiue,Hui-Ling Lee,Pinpin Lin,Hsiu-Yuan Yang,Chien-Tien Su,Yu-Mei Hsueh,'4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism-related enzymes gene polymorphisms, NNK metabolites levels and urothelial carcinoma',Toxicology Letters.16-22,2013-01
2013.12 Hui-Yi Liao,Yu-Teh Chung, Ching-Huang Lai,Shu-Li Wang,Hung-Che Chiang, Lih-Ann Li, Tsui-Chun Tsou,Wan-Fen Li, Hui-Ling Lee,Saou-Hsing Liou,'Six-month follow-up study of health markers of nanomaterials among workers handling engineered nanomaterials',Nanotoxicology.1-11,2013.12
2013.07 Chien-Yu Lin,Hui-Ling Lee,Yu-Chuan Chen,Guang-Wen Lien,Lain-Yu Line,Li-Li Wen,Chien-Chang Liao, Kuo-Liong Chien,Fung-Chang Sung, Pau-Chung Chen,'Positive association between urinary levels of 8-hydroxydeoxyguanosine and the acrylamide metabolite N-acetyl-S-(propionamide)-cysteine in adolescents and young adults',Journal of Hazardous Materials.372-377,2013.07
2012-06 Jui-Pin Wu,Mei-Hui Li,Jhih-Sheng Chen,Hui-Ling Lee,'In vivo and in vitro metabolism of tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK),by the freshwater planarian, Dugesia japonica ',Chemosphere,vol87.1341-1347,2012-06
2012-06 Chien-Kai Wang,Hui-Ling Lee,Han Chang,Ming-Hsien Tsai,Yu-Chun Kuo,Pinpin Lin,'Enhancement between environmental tobacco smoke and arsenic on emphysema-like lesions in mice',Journal of Hazardous Materials.256-263,2012-06
2012.11 Chia-Chang Wu,Chien-Tien Su,Hui-Ling Lee,Chi-Jung Chung,Chao-Yuan Huang,Yeong-Shiau Pu,Pinpin Lin,Yu-Mei Hsueh,'Joint Effect of Arsenic Methylation Profile and NNK Metabolites on Urothelial Carcinoma',THE JOURNAL OF UROLOGY,vol188.1701-17055,2012.11
2012.08 Saou-Hsing Liou,Tsui-Chun Tsou,Shu-Li Wang,Lih-Ann Li,Hung-Che Chiang,Wan-Fen Li,Pin-Pin Lin,Ching-Huang Lai,Hui-Ling Lee ,Ming-Hsiu Lin,'Epidemiological study of health hazards among workers handling engineered nanomaterials',Journal of Nanoparticle Research ,vol14.878-893,2012.08
2012.05 C.L. Su,D.W. Yuan,L.L. Chiang,H.L. Lee,K.H. Chen,D. Wang,'Inducible Cyclooxygenase Expression Mediating Hypoxia/Reoxygenation–Induced Pulmonary Vasoconstriction is Attenuated by a Cyclooxygenase Inhibitor in Rats',Transplantation Proceedings.929-932,2012.05
2012.02 Jein-Wen Chen ,Shu-Li Wang,Dannis Paul Hsientan,Hsi-Hsien Yang,Hui-Ling Lee,'Carcinogenic potencies of polycyclic aromatic hydrocarbons for back-door neighbors of restaurants with cooking emissions',Science of the Total Environment.68-75,2012.02
2012.01 Hung-Che Chiang,Yung-Kai Huang,Pei-Fen Chen,Chia-Chi Chang,Chien-Jen Wang,Pinpin Lin,Hui-Ling Lee,'4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone is correlated with 8-hydroxy-2'-deoxyguanosine in humans after exposure to environmental tobacco smoke',Science of the Total Environment ,vol414.134-139,2012.01
2011.11 Chien-Jen Wang,Ning-Hsiang Yang,Chia-Chi Chang,Saou-Hsing Liou,Hui-Ling Lee,'Rapid and simple one-step membrane extraction for the determination of 8-hydroxy-2’-deoxyguanosine in human plasma by a combination of on-line solid phase extraction and LC–MS/MS',Journal of Chromatography B,vol879.3538-3543,2011.11
2011.06 Huai-chih Chiang,Chin-Ying Wang,Hui-Ling Lee,Tsui-Chun Tsou,'Metabolic effects of CYP2A6 and CYP2A13 on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced gene mutation - a mammalian cell-based mutagenesis approach',Toxicology and Applied Pharmacology.145-152,2011.06
2011.02 Hui-Lin Lee,Chi-Jung Chung,Hsiu-Yuan Yang,Pinpin Lin,Yeong-Shiau Pu,Horng-Sheng Shiue,Chien-Tien Su,Yu-Mei Hsueh,'Low ratio of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol-glucuronides (NNAL-Gluc)/free NNAL increases urothelial carcinoma risk',Science of the Total Environment .1638-1642,2011.02
2011.01 Hui-Ling Lee,Dennis P.H. Hsieh,Lih-Ann Li,'Polycyclic aromatic hydrocarbons in cigarette sidestream smoke particulates from a Taiwanese brand and their carcinogenic relevance',chemosphere,vol82.477-482,2011.01
2010.08 Chien-Jen Wang,Ning-Hsiang Yang,Saou-Hsing Liou,李慧玲,'Fast quantification of the exhaled breath condensate of oxidative stress 8-iso-prostaglandin F2 using on-line solid-phase extraction coupled with liquid chromatography/electrospray ionization mass spectrometry',vol82.1434-1438,2010.08
2010.06 Hsien-Yu Cheng,Show-Chuen Chen,Hui-Ling Lee,'Fast Analysis of Phenolic Acids by Microchip Capillary Electrophoresis with Serpentine Channel and End Wrapped Electrode',vol57.371-377,2010.06
2010.04 ,李慧玲,vol51.315-321,2010.04