期刊論文
| 期間 |
內容 |
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2007-present |
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Wang KC, Ojeda NB, Wang H, Chiang HS, Tucci MA, Lee JW, Wei HC, Kaizaki-Mitsumoto A, Tanaka S, Dankhara N, Tien LT*, Fan LW*. Neonatal brain inflammation enhances methamphetamine-induced reinstated behavioral sensitization in adult rats analyzed with explainable machine learning. Neurochem Int. 2024 Jun;176:105743. (SCI) |
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Cheng YC, Huang CJ, Ku WC, Guo SL, Tien LT, Lee YJ, Chieh CC. Downregulated Calcium Binding Protein S100A16 and HSP27 in Placenta Derived Multipotent Cells Induce Functional Astrocyte Differentiation. Stem Cell and Reports. Jan 21. 2022 (SCI) |
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Yeh JH, Wang KC, Kaizaki A, Lee JW, Wei HC, Tucci MA, Ojeda NB, Fan LW, Tien LT*.
Pioglitazone Ameliorates Lipopolysaccharide-Induced Behavioral Impairment, Brain Inflammation, White Matter Injury and Mitochondrial Dysfunction in Neonatal Rats Int. J. Mol. Sci. 22(12), 6306, 2021. (SCI) |
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Rains ME, Muncie CB, Pang Y, Fan LW, Tien LT*, Djeda NB*.
Oxidative stress and neurodevelopmental outcomes in rat offspring with intrauterine growth restriction induced by reduced uterine perfusion.
Brain Sciences. 11: 78, 2021. (SCI) |
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Hsieh CT, Lee YJ, Lee JW, Lu S, Tucci MA, Dai X, Ojeda NB, Lee HJ, Fan LW, Tien LT*,Interleukin-1 receptor antagonist ameliorates the pain hypersensitivity, spinal inflammation and oxidative stress induced by systemic lipopolysaccharide in neonatal rats. Neurochem Int. 135:104686. 2020 (SCI) |
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Hsieh CT, Lee YJ, Dai X, Ojeda NB, Lee HJ, Tien LT*, Fan LW. Systemic lipopolysaccharide induced pain sensitivity and spinal inflammation were reduced by minocycline in neonatal rats. Int. J. Mol. Sci. 19(10):2947-2962, 2018 (SCI) |
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Tien LT, Lee YJ, Pang Y, Lu S, Lee JW, Tseng CH, Bhatt AJ,
Savich RD, Fan LW. Neuroprotective effects of intranasal IGF-1 against neonatal
lipopolysaccharide-induced neurobehavioral deficits and neuronal inflammation in the substantia nigra and locus coeruleus of juvenile rats. Developmental Neuroscience. 39(6): 443-459, 2017. (SCI) |
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Chien CC, Huang CJ, Tien LT, Cheng YC, Ke CY, Lee YJ*.
Suppression of HSP27 restores retinal function and protects photoreceptors from
apoptosis in a light-induced retinal degeneration animal model. Investigative
Ophthalmology & Visual Science, 58: 3107-3117, 2017. (SCI) |
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Lu S, Sfaffery JP, Pang Y, Tien LT, Fan LW. Rapid Eye Movement
Sleep Homeostatic Response: A Potential Marker for Early Detection of
Parkinson’s Disease. J Alzheimer’s Dis Parkinsonism. 6: 255, 2016 |
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Cheng YC, Huang CJ, Lee YJ, Tien LT, Ku WC, Chien R, Lee FK,
Chien CC*. Knocking down of heat-shock protein 27 directs differentiation of
functional glutamatergic neurons from placenta-derived multipotent cells. Sci
Rep. 6:30314. 2016 (SCI) |
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Lin SH, Huang YN, Kao JH, Tien LT, Tsai RY, Wong CS*. Melatonin reverses morphine tolerance by inhibiting microglia activation and HSP27 expression. Life Sci. 152: 38-43. 2016 (SCI) |
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Lan KM#,Tien LT#, Cai Z*, Lin S, Pang Y, Tanaka S, Rhodes PG,
Bhatt A, Savich RD, Fan LW*. Erythropoietin ameliorates neonatal hypoxia-
schemia-induced neurobehavioral deficits, neuroinflammation, and hippocampal
injury in the juvenile rat. Int. J. Mol. Sci. 17: 289-307. 2016 (SCI) |
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Pang Y, Tien LT, Zhu H, Shen J, Wright C, Jones T, Mamoon S,
Bhatt A, Cai Z, Fan LW*. Interleukin-1 receptor antagonist reduces neonatal
lipopolysaccharide-induced long-lasting neurobehavioral deficits and
dopaminergic neuronal injury in adult rats. Int. J. Mol. Sci. 16: 8635-8654. 2015 (SCI) |
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Lan KM#,Tien LT#, Pang Y, Bhatt A, Fan LW*. IL-1 receptor
antagonist attenuates neonatal lipopolysaccharide-induced long-lasting learning
impairment and hippocampal injury in adult rats. Toxicology Letters. 234: 30-39. 2015 (SCI) |
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Fan LW, Bhatt A, Tien LT, Zheng B, Simpson KL, Lin R, Cai Z,
Kumar P, Pang Y*. Exposure to serotonin adversely affects oligodendrocyte
development and myelination in vitro. J Neurochem. 133: 532-543. 2015 (SCI) |
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Wong CS, Jow GM, Kaizaki A, Fan LW, Tien LT*. Melatonin
ameliorates brain injury induced by systemic lipopolysaccharide in neonatal
rats. Neuroscience. 267: 147-156, 2014 (SCI) |
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Wong CS, Lee YJ, Chiang YC, Fan LW, Ho IK,Tien LT*. Effect of
prenatal methadone on reinstated behavioral sensitization induced by
methamphetamine in adolescent rats. Behav Brain Res. 258: 160-165. 2014 (SCI) |
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Tien LT, Kaizaki A, Pang Y, Cai Z, Bhatt AJ, Fan LW*. Neonatal
exposure to lipopolysaccharide enhances accumulation of alpha-synuclein
aggregation and dopamine transporter protein expression in the substantia nigra
in responses to rotenone challenge in later life. Toxicology. 308: 96-103. 2013 (SCI) |
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Pang Y*, Fan LW, Tien LT, Dai X, Zheng B, Cai Z, Lin RC, Bhatt
A. Differential roles of astrocyte and microglia in supporting oligodendrocyte
development and myelination in vitro. Brain Behav. 3: 503-514, 2013. (SCI) |
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Kaizaki A, Tien LT, Pang Y, Cai Z, Tanaka S, Numazawa S, Bhatt
AJ, Fan LW*. Celecoxib reduces brain dopaminergic neuronal dysfunction, and
improves sensorimotor behavioral performance in neonatal rats exposed to
systemic lipopolysaccharide. J Neuroinflammation. 10: 45-59. 2013 (SCI) |
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Fan LW*, Kaizaki A,Tien LT, Pang Y, Tanaka S, Numazawa S, Bhatt AJ, Cai Z. Celecoxib attenuates systemic lipopolysaccharide-induced brain
inflammation and white matter injury in the neonatal rats. Neuroscience. 240:
27-38. 2013 (SCI) |
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Cai Z*, Fan LW, Kaizaki A, Tien LT, Ma T, Pang Y, Lin S, Lin R, Simpson KL. Neonatal systemic exposure to lipopolysaccharide enhances
susceptiblity of nigrostriatal dopaminergic neurons to rotenone neurotoxicity in later life. Dev. Neurosci. 35: 155-171, 2013. (SCI) |
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Wang KC, Fan LW, Kaizaki A, Pang Y, Cai Z, Tien LT*. Neonatal
lipopolysaccharide exposure induces long-lasting learning impairment, less
anxiety-like response and hippocampal injury in adult rats. Neuroscience. 234:
146-157, 2013. (SCI) |
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Tsai MD, Chen PR, Tien LT, Cai YJ, Lee YJ*. Nuclear
condensation and cell cycle arrest induced by telomerase siRNA in neuroblastoma
cells. J Neurooncol. 111: 265-272, 2013. (SCI) |
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Wang KC, Lee YJ, Fan LW, Yang PP, Tao PL, Ho IK, Tien LT*. Mu-
opioid receptor knockout mice are more sensitive to chlordiazepoxide-induced
anxiolytic behavior. Brain Res. Bull. 90: 137-141, 2013. (SCI) |
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Hsiao WT, Tsai MD, Jow GM, Tien LT, Lee YJ*. Involvement of
Smac, p53, and caspase pathways in induction of apoptosis by gossypol in human
retinoblastoma cells. Molecular Vision. 18: 2033-2042, 2012. (SCI) |
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Chien CC, Lee YJ, Fan LW, Ho IK, Tien LT* Naloxonazine, a
specific mu-opioid receptor antagonist, attenuates the increment of locomotor
activity induced by acute methamphetamine in mice. Toxicology Letters. 212: 61-
65, 2012 (SCI) |
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Park SW, Shen X, Tien LT, Roman R, Ma T. Methamphetamine-
induced changes in the striatal dopamine pathway in mu-opioid receptor knockout
mice. J Biomed Sci. 18: 83, 2011 (SCI) |
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Fan LW, Tien LT, Lin RC, Simpson KL, Rhodes PG, Cai Z*.
Neonatal exposure to lipopolysaccharide enhances vulnerability of nigrostriatal
dopaminergic neurons to rotenone neurotoxicity in later life. Neurobiol. Dis.
44: 304-316. 2011 (SCI) |
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Tien LT, Cai Z, Rhodes PG, Fan LW*. Neonatal exposure to
lipopolysaccharide enhances methamphetamine-induced reinstated behavioral
sensitization in adult rats. Behavioural Brain Research. 224: 166-173. 2011
(SCI) |
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Ku TH, Lee YJ, Wang SJ, Fan CH, Tien LT*. Effect of honokiol on activity of GAD65 and GAD67 in the cortex and hippocampus of mice.
Phytomedicine. 18: 1126-1129. 2011. (SCI) |
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Tien LT. Ho IK*. Involvement of mu-opioid receptor in
methamphetamine-induced behavioral sensitization. Review. Current
Neuropharmacology. 9: 215-218, 2011. (SCI) |
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Wang KC, Wang SJ, Fan LW, Cai Z, Rhodes PG, Tien LT*.
Interleukin-1 receptor antagonist ameliorates neonatal lipopolysaccharide-
induced long-lasting hyperalgesia in the adult rats. Toxicology. 279: 123-129.
2011. (SCI) |
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Fan LW, Tien LT, Zheng B, Pang Y, R Lin, KL Simpson, T Ma,
Rhodes P, Cai Z*. Dopaminergic neuronal injury in the adult rat brain following
neonatal exposure to lipopolysaccharide and the silent neurotoxicity. Brain,
Behavior, and Immunity. 25: 286-297. 2011. (SCI) |
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Fan LW, Tien LT, Zheng B, Pang Y, Rhodes P, Cai Z*.
Interleukin-1 beta-induced brain injury and neurobehavioral dysfunctions in
juvenile rats can be attenuated by alpha-phenyl-N-tert-Butyl-Nitrone.
Neuroscience. 168: 240-252. 2010. (SCI) |
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Shen X, Purser C, Tien LT, Chiu CT, Pual IA, Baker R, Loh HH,
Ho IK, Ma T*. The μ-opioid receptor knockout mice are insensitive to
methamphetamine-induced behavioral sensitization. Journal of Neuroscience
Research. 88: 2294-2302. 2010. (SCI) |
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Tien LT, Ho IK, Ma T*. Methamphetamine-induced expression of
zif268 mRNA is prevented by haloperidol in mice lacking mu-opioid receptor.
Neurotoxicology. 31:326-330. 2010. (SCI) |
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Fan LW, Mitchell H, Tien LT, Rhodes PG, Cai Z*. Interleukin-1
beta-induced brain injury in the neonatal rat can be ameliorated by alpha-
phenyl-n-tertbutyl-nitrone. Exp Neurol. 220:143-153. 2009. (SCI) |
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Tsai YJ, Lin CT, Huang CT, Wang HY, Tien LT, Chen SH, Lue JH*.
Neuropeptide Y modulates c-Fos protein expression in the Cuneate nucleus and
contributes to mechanical hypersensitivity following rat median nerve injury. J. of Neurotrauma. 26: 1609-1621. 2009. (SCI) |
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Lin TY, Lu CW, Tien LT, Chuang SH, Wang YR, Chang WH, Wang SJ*. Fangchinoline inhibits glutamate release from rat cerebral cortex nerve
terminals (synaptosomes). Neurochem Int. 54:506-512. 2009. (SCI) |
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Cheng CK, Peng PH, Tien LT, Cai YJ, Chen CF, Lee YJ*.
Bevacizumab is not toxic to retinal ganglion cells after repeated intravitreal
injection. Retina. 29: 306-312. 2009. (SCI) |
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Fan LW, Tien LT, Mitchell HJ, Rhodes PG, Cai Z*. Alpha-phenyl-
n-tert-butyl-nitrone ameliorates hippocampal injury and improves learning and
memory in juvenile rats following neonatal exposure to lipopolysaccharide. Eur.
J. Neurosci. 27:1475-1484. 2008. (SCI) |
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Fan LW, Mitchell HJ, Tien LT, Zheng B, Pang Y, Rhodes PG, Cai
Z*. alpha-Phenyl-n-tert-butyl-nitrone reduces lipopolysaccharide-induced white
matter injury in the neonatal rat brain. Dev. Neurobiol. 68(3):365-78. 2008. (SCI) |
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Chou CW, Huang WT, Tien LT, Wang SJ*. (-)-Epigallocatechin
gallate, the most active polyphenolic catechin in green tea, presynaptically
facilitates Ca2+-dependent glutamate release via activation of protein kinase C
in rat cerebral cortex. Synapse. 61: 889-902, 2007. (SCI) |
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Tien LT*, Ma T, Fan LW, Loh HH, Loh HH. Autoradiographic
analysis of GABAA receptors in mu-opioid receptor knockout mice. Neurochem Sci.
32: 1891-1897, 2007. (SCI) |
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Tien LT, Ho IK, Loh HH, Ma T*. Role of mu-opioid receptor in
modulation of preproenkephalin mRNA expression and opioid and dopamine receptor
binding in methamphetamine-sensitized mice. J Neurochem. Sci. 85: 673-680, 2007. (SCI) |
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研討會論文
| 期間 |
內容 |
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2007-present |
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Lee YJ, Chien CC, Huang CJ, Ke CY, Tien LT, Lin PK, Cheng YC. Long-term light expose upregulates
expression of transcription factor AP-2 delta by activating IL1B and IL8 in retinal epithelial cells
Abstract 546.03 Society for Neuroscience, 2023 (U.S.A.) |
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Quach VV, Lee JW, Arunachalam AI, Herris MC, Cooper AN, Turbeville EC, Lee N, Arguello I, Dankhara N, Tien LT, Fan LW, Ojeda NB. Both maternal inflammation and intrauterine growth restriction enhance susceptibility to ischemic stroke- induced brain injury and neurobehavioral dysfunction in rats.
39th Southern Biomedical Engineering Conference, 2023. (U.S.A.) |
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Tien LT. Pioglitazone 可降低酯多醣所造成的腦部發炎與行為缺失. 2022年發光科學在醫學與光電的應用研討會. 2022.10.15台灣台北 |
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Tien LT, Lee JW, Ojeda NB, Tucci MA, Fan B, Fan LW. Intranasal insulin reduces brain inflammation and improves neurobehavioral performance following lipopolysaccharide exposure in neonatal rats. 38th Southern Biomedical Engineering Conference, 2022 |
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Wei HC, Tien LT, Fan LW. PPARɣ receptor agonist protects against LPS-Induced brain injury in neonatal rats. 37th Southern Biomedical Engineering Conference, 2021 |
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Tien L, Lee Y, Lee J, Fan L. Neonatal systemic exposure to lipopolysaccharide enhances methamphetamine-induced sensitization in later life. 36th Southern Biomedical Engineering Conference, 2020. |
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Fan L, Tien L., Lee J, Lu S., Dankhara N., Prakash V., Arguello I., Pang Y., Bhatt A., Savich R., Ojeda N. Inflammation exacerbates intrauterine growth restriction-induced cognitive deficits in juvenile rats, Abstract 641.22.
Society for Neuroscience, 2019. |
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Tien L., Lee Y., Fan L. Intranasal IGF-1 reduced neonatal LPS-induced behavioral deficits and inflammation in juvenile rats, Abstract a90724,
FAOPS2019 |
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Tien L., Lee Y., Fan L. Systemic lipopolysaccharide induced spinal inflammation associated allodynia and hyperalgesia were reduced by minocycline in neonatal rats Abstract 660.11. Society for Neuroscience, 2018. |
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Tien L., Lee Y., Fan L. Intranasal IGF-1 protects against neonatal lipopolysaccharide-induced neurobehavioral deficits and neuronal inflammation in the brain. Abstract F18-2880. 11th FENS, 2018. |
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Tien L., Wong C., Chiang Y., Ku W., Fan L., Ho I. Prenatal methadone on behavioral sensitization induced by methamphetamine in adolescent rats. 5th APSAAR and TSAS 2017 |
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Tien L., Lan L, Pang Y., Lu S., Bhatt A., Fan L. IL-1 receptor antagonist protects against long-lasting learning impairment and hippocampal injury in adult rats following neonatal exposure to lipopolysaccharide. 33rd Southern Biomedical Engineering Conference 2017.03.16 |
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Tien LT, Lan KM, Pang Y, Lu S, Bhatt AJ, Fan LW. IL-1 receptor antagonist
protects against long-lasting learning impairment and hippocampal injury in
adult rats following neonatal exposure to lipopolysaccharide. The 33rd Annual
Southern Biomedical Engineering Conference (U.S.A.). 2017. |
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Fan LW, Tien LT, Lee JW, Lu S, Lin RCS, Dai X, Ojeda NB, Bhatt AJ, Pang Y.
Neonatal exposure to interleukin-1beta enhances adult vulnerability to rotenone
neurotoxicity in the nigrostriatal dopaminergic system. Abstract 606.22 Society
for Neuroscience (U.S.A.). 2016. |
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Tien LT, Pang Y, Lu S, Lee JW, Lin S, Bhatt AJ, Savich RD, Fan LW. Neonatal
systemic exposure to lipopolysaccharide enhances adult vulnerability to paraquat neurotoxicity. Abstract 2345. Society of Toxicology (U.S.A.). 2016 |
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Tien LT, Lee Y, Lee JA, Fan LW. Neonatal lipopolysaccharide-induced long-rasting
neurobehavioral deficits and dopaminergic neuronal injury was attenuated by IL-1 receptor antagonist in adult rats. Abstract 74.14. Society for Neuroscience (U.S.A.). 2015. |
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Tien LT, Lee Y, Fan LW. Melatonin ameliorates brain injury induced by systemic
lipopolysaccharide in neonatal rats. Abstract 528.15. Society for Neuroscience
(U.S.A.). 2014. |
| |
Tien LT, Wong C, Lee YJ, Chiang YC, Fan LW, Ho IK. Effect of prenatal methadone
on reinstated behavioral sensitization induced by methamphetamine in adolescent
rats. Abstract 369. Society of Toxicology (U.S.A.). 2014. |
| |
Tien LT, Wang KC, Fan LW, Kaizaki A, Pang Y, Cai Z. A long-lasting learning
impairment, less anxiety-like response and hippocampal injury in adult rats
following a neonatal lipopolysaccharide exposure. Abstract 725.04. Society for
Neuroscience (U.S.A.). 2013. |
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Tien LT, Kaizaki A, Pang Y, Cai Z, Fan LW. Neonatal exposure to
lipopolysaccharide enhances dopamine transporter protein expression and
accumulation of alpha-synuclein aggregation in the substantia nigra in responses to rotenone challenge in later life. Abstract 660.02. Society for Neuroscience (U.S.A.). 2012. |
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Tien LT, Lee YJ, Ho IK. Naloxonazine, specific mu-opioid receptor antagonist,
inhibits locomotor activity induced by methamphetamine in mice. Abstract 81.10.
Society for Neuroscience (U.S.A.). 2011. |
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Tien LT, Cai Z, Rhodes P, Fan LW. Neonatal exposure to lipopolysaccharide
enhances methamphetamine-induced behavioral sensitization in adult rats.
Abstract 879.10.Society for Neuroscience (U.S.A.). 2010. |
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Tien LT, Lee YJ. Change in down-stream signaling of striatal dopaminergic
transmission in methamphetamine-sensitized mice. Abstract 7914. Experimental
Biology (U.S.A.). 2010. |
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Tien LT, Wang KC, Wang SJ, Fan CH, Fan LW, Rhodes P, Z. Cai. Lipopolysaccharide-
induced long-lasting hyperalgesia was reduced by interleukin-1 receptor
antagonist in rats. Abstract 338.16 Society for Neuroscience (U.S.A.). 2009. |
| |
Tien LT, Fan LW, Zheng B, Pang Y, Rhodes P, Cai Z. Disturbance of motor behavior and dopaminergic injury in the adult rat brain following neonatal exposure to lipopolysaccharide. Abstract 652.1 Society for Neuroscience (U.S.A.). 2008. |
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Tien LT, Ho IK, Loh HH, Ma T. Role of μ-opioid receptor in modulation of
immediate-early gene zif268 mRNA expression in methamphetamine-sensitized mice.
Abstract 911.3. Society for Neuroscience (U.S.A.), 2007. |
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Tien LT, Lee YJ, Ho IK, Loh HH, Ma T. Modulation of mu-opioid receptor in
preproenkephalin mRNA expression and opioid and dopamine receptor binding in
methamphetamine-sensitized mice. Japanese Society of Toxicology. 2007. |
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