學歷
學校 系所 學位
陽明大學 生理學研究所 博士
經歷
期間 單位 部門 職稱
美國肯塔基大學 生理系 訪問學者
中山醫學大學 生理科 助理教授
專長
呼吸生理學
學術著作
期刊論文
期間 內容
Liu BY, Lin YJ, Lee HF, Ho CY, Ruan T*, Kou YR*. Menthol suppresses laryngeal C-fiber hypersensitivity to cigarette smoke in a rat model of gastroesophageal reflux disease: the role of TRPM8. Journal of Applied Physiology 2015, 118: 635-645.
Lin YJ, Lin RL, Ruan T, Khosravi M, Lee LY. A synergistic effect of simultaneous TRPA1 and TRPV1 activations on vagal pulmonary C-fiber afferents. Journal of Applied Physiology 2015, 118: 273-281.
Ruan T, Lin YJ, Hsu TH, Lu SH, Jow GM, Kou YR*. Sensitization by pulmonary reactive oxygen species of rat vagal lung C-fibers: the roles of the TRPV1, TRPA1, and P2X receptors. PLOS ONE 2014, 9, e91763.
Peng HY, Yeh CM, Cheng JK, Chau YP, Ruan T, Chen GD, Hsieh MC, Lai CY, Lin TB. Acute Uterine Irritation Provokes Colonic Motility via Transient Receptor Potential A1-dependent Spinal NR2B Phosphorylation in Rats. Anesthesiology 2014, 120: 436-446.
Lin YJ, Hsu HH, Ruan T*, Kou YR*. Mediator mechanisms involved in TRPV1, TRPA1 and P2X receptor-mediated sensory transduction of pulmonary ROS by vagal lung C-fibers in rats. Respiratory Physiology & Neurobiology 2013, 189: 1-9.
Lin YJ, Lin YS, Lai CJ, Yuan ZF, Ruan T*, Kou YR*. Perivagal antagonist treatment in rats selectively blocks the reflex and afferent responses of vagal lung C-fibers to intravenous agonists. Journal of Applied Physiology 2013, 114: 361-370.
Shen MY, Luo YL, Ynag CH, Ruan T, Lai CJ*. Hypersensitivity of lung vagal C fibers induced by acute intermittent hypoxia in rats: role of reactive oxygen species and TRPA1. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2012, 303: R1175-R1185.
Hsu HH, Ruan T, Ko WJ, Hsu JY, Chen JS, Lee YC, Lai IR, Chen CF*. Effects of simvastatin on pulmonary C-fiber sensitivity in rats with monocrotaline-induced pulmonary hypertension. Journal of Heart and Lung Transplantation 2011, 30: 332-340.
Hsu CC, Bien MY, Huang YT, Ruan T, Kou YR*, Lin YS*. N-arachidonyl dopamine sensitizes rat capsaicin-sensitive lung vagal afferents via activation of TRPV1 receptors. Respiratory Physiology & Neurobiology 2009, 167: 323-332.
Ruan T, Lin YS, Lin KS, Kou YR*. Mediator mechanisms involved in TRPV1 and P2X receptor-mediated, ROS-evoked bradypneic reflex in anesthetized rats. Journal of Applied Physiology 2006, 101: 644-654.
Ruan T, Lin YS, Lin KS, Kou YR*. Sensory transduction of pulmonary reactive oxygen species by capsaicin-sensitive vagal lung afferent fibres in rats. Journal of Physiology-London 2005, 565: 563-578.
Ruan T, Gu Q, Kou YR, Lee LY*. Hyperthermia increases sensitivity of pulmonary C-fibre afferents in rats. Journal of Physiologyy-London 2005, 565: 295-308.
Lai CJ, Ruan T, Kou YR*. The involvement of hydroxyl radical and cyclooxygenase metabolites in the activation of lung vagal sensory receptors by circulatory endotoxin in rats. Journal of Applied Physiology 2005, 98: 620-628.
Wu ZX, Yang QH, Ruan T, Lee LY*. Influence of maturation on constrictive response to stimulation of C-fiber afferents in isolated guinea pig airways. American Journal of Physiology - Lung Cellular & Molecular Physiology 2004, 287: L168-L175.
Ruan T, Ho CY, Kou YR*. Afferent vagal pathways mediating respiratory reflexes evoked by reactive oxygen species in the lungs of anesthetized rats. Journal of Applied Physiology 2003, 94: 1987-1998.
Gu Q, Ruan T, Hong JL, Burki N, Lee LY*. Hypersensitivity of pulmonary C fibers induced by adenosine in anesthetized rats. Journal of Applied Physiology 2003, 95:1315-1324.
研討會論文
期間 內容
Lin YJ, Ruan T*, Kou YR*. Selective blockades of agonist-induced reflex and afferent responses of vagal lung C-fibers by perivagal antagonist treatment in rats. International Conference of Experimental Biology, 2013, Boston, USA.
Yeh CM, Lin YJ, Ruan T*, Hsu TH*. Genistein attenuates reactive oxygen species-enhanced airway reflex reactivity in rats. The 26th Joint Annual Conference of Biomedical Sciences, 2011, Taipei, Taiwan.
Ruan T, Chong WY, Ko PJ, Lin TB, Kou YR*. Estrogen alleviates enhanced airway reflex reactivity induced by increased lung reactive oxygen species in female rats. International Conference of Experimental Biology, 2010, San Diego, USA.
Ruan T, Lin YJ, Lin TB, Kou YR*. Augmentation of vagal C-fiber afferent-mediated airway reflex reactivity by pulmonary reactive oxygen species in anesthetized rats. International Union of Physiological Sciences, 2009, Kyoto, Japan.
Ruan T, Lin TB, Kou YR*. Mediator mechanisms involved in TRPV1 and P2X receptor-mediated, ROS-evoked excitation of capsaicin-sensitive vagal lung afferent fibers in rats. International Conference of American Thoracic Society, 2008, Toronto, Canada.
Ruan T, Lin YJ, Ngieng SL, Lin TB, Kou YR*. Pulmonary reactive oxygen species augment the airway reflex mediated by lung vagal C-fiber afferents in rats. The 23th Joint Annual Conference of Biomedical Sciences, 2008, Taipei, Taiwan.
Ruan T, Lin TB, Kou YR*. Mediator mechanisms underlying the sensory transduction of pulmonary reactive oxygen species by capsaicin-sensitive vagal lung afferent fibers in rats. The 22th Joint Annual Conference of Biomedical Sciencse, 2007, Taipei, Taiwan.
Weng HT, Ruan T, Kou YR*. The involvement of hydroxyl radical and P2X receptors in the sensory transduction of inhaled cigarette smoke by capsaicin-sensitive vagal lung afferent fibers in rats. The 22th Joint Annual Conference of Biomedical Sciencse, 2007, Taipei, Taiwan.
Ruan T, Lin YS, Lin KS, Kou YR*. Sensory transduction of reactive oxygen species by vagal lung afferent C fibers in rats: role of VR1 receptors. The 20th Joint Annual Conference of Biomedical Sciences, 2005, Taipei, Taiwan.
Ruan T, Lee LY*. Hyperthermia increases the sensitivity of pulmonary c-fiber afferents to chemical and mechanical stimulation in anesthetized rats. International Conference of American Thoracic Society, 2004.
Ruan T, Lin YS, Lee LY*. Effect of 5-hydroxytryptamine (5-HT) on pulmonary mechanoreceptors in anesthetized rats. International Conference of American Thoracic Society, 2003.
Lin YS, Ruan T, Lee LY*. Stimulation of pulmonary C-fiber afferents by 5-hydroxytryptamine (5-HT) in anesthetized rats: role of 5-HT3 receptors. International Conference of American Thoracic Society, 2003.
Ruan T, Kou YR*. Activation of lung vagal sensory receptors by aerosolized hydrogen peroxide in rats. International Conference of American Thoracic Society, 2002.
Ruan T, Kou YR*. Roles of lung vagal unmyelinated and myelinated afferents in the H2O2-evoked airway reflexes in rats. International Conference of Experimental Biology, 2001.
Ruan T, Kou YR*. H2O2-evoked airway reflexes in rats: neural and chemical mechanisms. International Conference of Experimental Biology, 2000.
研究計畫
期間 主持人 計畫名稱 贊助單位 贊助金額 職稱
探討食道炎症反應引發呼吸道過度反應之跨臟器反射敏感機制(國科會102)
鎳在台灣不抽菸肺癌形成之角色之子計畫四(國科會101)
雌激素在活性氧族群引發呼吸道過度敏感的角色(國科會98-102)
活性氧族群造成大白鼠呼吸道過度反應的神經與介質機轉(國科會96-98)
其他教學經驗
其他教學經驗
期間 內容
自然科技(通識)/人體的奧秘
呼吸治療學系/生理學實驗
營養科學系/人體生理學
職能治療學系/生理學
護理學系碩士班/進階病理生理學(一)